DPCstruct | MC10952

Metacluster Properties and Pfam Annotations

Number of structural domains210
Mean domain length (aa)324 ± 51 aa
Standard deviation of domain lengths50.76
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.18
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)17.30
Pfam Score95.18
Assigned Pfam label(s) CL0409- CL0020- PF12004- PF08337

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7KDH1 42-291 MEKIMPEEEYSEFKEMILQKDFHAIYALANVCGQDRTLLASLLLRIFRHEKAEAPLLRTLNDREINMEDEATTLFRATTLASTLMEQ…
A0A0L0D6T2 14-337 EGLLDVLLDDEMQLVEAIVSQMDICDADKLAKIFVHCFESRDMTLQLLERSVTREIEKTEYAQVLFRGNSLASKMMTVYSRLVGTQY…
A0A397F370 12-234 None
A0A1I8IG18 168-516 None
A0A0K0E8N7 771-1095 None
A0A7R9KZL5 756-1076 None
C3ZF12 232-463 None
C4LU33 17-379 None
C4LUL5 12-311 None
F4PK80 303-628 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.