DPCstruct | MC10951

Metacluster Properties and Pfam Annotations

Number of structural domains537
Mean domain length (aa)314 ± 72 aa
Standard deviation of domain lengths72.32
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score80.59
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)15.30
Pfam Score77.76
Assigned Pfam label(s) CL0270- CL0500- CL0277- PF04621- CL0109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0L0D660 109-447 MNDEPVVRVPLKRLGLIVNPLSGNKKGVRIVSDILRPVFEDEFGIEVKVFETEYAGHAVVLAETIDTSKLDGLVVAGGDGSFHEVVN…
A0A1E3TG71 1-200 MNTTVLVFGAGRLPRALRGLPVAQVDSAVETARRLIVVGSDADLAGVLTRLLRADRLDVEVAYVSRRRSPATRAYRLATRWRAARRA…
A0A0K0EBU9 1115-1478 None
A0A1I8IVF2 5-290 None
A0A446Q137 2-230 None
A0A6I8VVH6 81-369 None
A0A1D2N9J9 889-1092 None
A0A7S4PPD8 117-474 None
A0A5B7DBT3 11-257 None
A0A7R9PPH4 2-317 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.