DPCstruct | MC1086

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)106 ± 18 aa
Standard deviation of domain lengths17.67
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.26
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)37.28
Pfam Score100.00
Assigned Pfam label(s) CL0028

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y3MFV5 13-108 LTHMVDWDALGGRSNGAEDRLRRHLTSASVLAVPPRPHTATAVIVGARRDGYIPPAAVKALHEHWPGSELRWLPGGHATMIWRQKDA…
S4PPV1 7-105 KIDISKIHWRDREALQFMRGIMDECTHLSNFSIPFDTSLIIAVCAKHDAYVPREDVGTLEEIWPGAEVRYVDAGHVSAYILHQSLFR…
A0A1B6LKQ6 166-297 None
B7Q0M7 95-208 None
A0A1Y1KE77 42-158 None
A0A183BBG2 27-128 None
H2YPB4 153-292 None
A0A817GPR6 245-368 None
A0A183TBB4 58-151 None
A0A654GMC8 227-343 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.