DPCstruct | MC1085

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)153 ± 22 aa
Standard deviation of domain lengths21.64
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score85.62
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)29.65
Pfam Score87.84
Assigned Pfam label(s) PF09435- PF04063- PF04064

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1PIK1 87-244 RRGGTIGILKNICFDPVYHDIILRDPDDILCALLYPLCGPEEFSDEENDMLPIDLQFLPETKTREEDPDLRKMLLESLLQLCSRRKS…
S4PNT5 6-147 RRSGMVRIVRNLSFDTSYHVFLLSEDLDLLSYLLPPIMGNEEYSDDEMEKLPAAVQYYSKDKRRDCVLEIRKEIIETLNKLCAKRHG…
A0A7R9ZPA1 16-150 None
A0A7S0YAG2 2-169 None
A0A7S2RP18 34-188 None
A0A3Q0KHM8 13-187 None
A0A1I7VHS3 6-113 None
A0A401RK92 68-225 None
K7H927 2-117 None
A0A0N1HEC9 197-350 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.