DPCstruct | MC10848

Metacluster Properties and Pfam Annotations

Number of structural domains155
Mean domain length (aa)109 ± 22 aa
Standard deviation of domain lengths21.52
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score84.33
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)17.24
Pfam Score71.33
Assigned Pfam label(s) CL0172- PF10780- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A151Z8C2 61-154 SHNLQEIRIHFCQSAQSSEGLRNFVVKNYSDIKKLNPKLPFLIREAHGIEPVIYARYDWGKEEKKVVTNLTEQEVEEKLKELCLLGN…
A0A452RUR7 25-126 QLQRLSFSLSRDAPSSRGAREFVEREVADFARRNAGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEIATLVQKLADQSGLE…
A0A811MS74 8-97 None
A0A199VTM8 3-109 None
M9LXE0 21-143 None
A0A0S8B094 6-124 None
A0A7R9KME6 580-710 None
A0A654HER3 145-234 None
M1VC65 15-132 None
A0A7S1QP37 8-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.