DPCstruct | MC10734

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)198 ± 26 aa
Standard deviation of domain lengths25.64
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.82
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)19.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L2FRK8 2-156 AELFYQTCPGDWQGDGAFLKECLKAAAWGNTNPDVTVDIGAFVSYRWKLILLADQLIEDLGLPVPGNQTCAMWNEYVWRGEVLYNLE…
A0A5M8PBT7 233-406 SGNTVVQAGSIRMSDTLTLPTAAARSALRNMAQKYFNSFPGDSSAATQHRVWVLCVDIVSNKNLPDSDLEFLSAALQFRLVKVVGMA…
S3C4J3 275-479 None
T0M241 21-269 None
A0A1B8ERP4 1-231 None
A0A101MNC5 14-203 None
Q2H4U4 360-543 None
D4DEB9 33-224 None
A0A1J7JGJ6 528-735 None
J3PDC7 343-559 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.