DPCstruct | MC10667

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)161 ± 35 aa
Standard deviation of domain lengths34.89
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.30
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.02
Pfam Score94.06
Assigned Pfam label(s) CL0125- PF20410- PF01510- CL0187- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q113W2 161-323 None
A0A2E2TMX3 789-911 None
A0A2E2VU94 36-212 None
A0A355JGK6 271-441 None
A0A3N0GS59 414-565 None
A0A0L6VYB8 90-240 None
A0A350Y7C3 38-168 None
A0A2N1TCB2 197-399 None
A0A2S5W8K7 40-185 None
A0A2G6EVH9 152-342 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.