DPCstruct | MC10667

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)161 ± 35 aa
Standard deviation of domain lengths34.89
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.30
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.02
Pfam Score94.06
Assigned Pfam label(s) CL0125- PF20410- PF01510- CL0187- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6M0BNL4 2-125 None
A0A239FSD9 71-279 None
A0A1Q8ZDL8 53-213 None
W1YPF7 72-270 None
A0A0G1TBV2 168-281 None
A0A0G1WAG5 430-597 None
A0A2Z4WGJ4 36-184 None
A0A2E4XW55 4-218 None
A0A7W8I4N5 510-690 None
A0A6G1X9A6 521-675 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.