DPCstruct | MC10667

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)161 ± 35 aa
Standard deviation of domain lengths34.89
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.30
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.02
Pfam Score94.06
Assigned Pfam label(s) CL0125- PF20410- PF01510- CL0187- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I1S3E2 47-222 None
E6TR46 825-977 None
W4UCT1 75-277 None
A0A417BBM7 146-280 None
A0A4T1ZT35 122-337 None
A0A218QHJ5 4-134 None
A0A1I5GEC9 106-271 None
K9FA69 899-1024 None
A0A7C6E8S6 2-146 None
A0A561E3A3 28-202 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.