DPCstruct | MC10667

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)161 ± 35 aa
Standard deviation of domain lengths34.89
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.30
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.02
Pfam Score94.06
Assigned Pfam label(s) CL0125- PF20410- PF01510- CL0187- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A350XFD0 89-252 None
A0A7Y5HG47 50-219 None
A0A2V5RQG9 351-533 None
A0A8B0EKR3 210-360 None
A0A6P0MKV4 5-152 None
A0A6P0MRA5 89-211 None
U5F726 196-361 None
A0A6B1L8W5 258-397 None
A0A845LW39 1-103 None
A0A2M6WTP6 347-502 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.