DPCstruct | MC10667

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)161 ± 35 aa
Standard deviation of domain lengths34.89
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score77.30
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)25.02
Pfam Score94.06
Assigned Pfam label(s) CL0125- PF20410- PF01510- CL0187- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W0KVA7 32-182 DPRCTVQVSLRRGDDVLDQVSCLKRHLQGRGLPASRDSRFGVDTVRAVRALGRAEGRPVDGIADSRLLKHLGAWSEPSHTRPPCTVS…
A0A8B2UWP1 2-97 TALIYALQRAIGMSSAQANGNYGPGTIAATPTVNQGANSDVVQVIQYGLYVNGFYTGAFDGYFSSDVATAVVAFRKFMNLPPFNSTA…
A0A7D4TPM5 211-344 None
A0A1E3GYY1 175-402 None
C4WK41 9-201 None
A0A7T5EWK3 214-363 None
A0A7V9DK96 490-635 None
A0A3M2HIH5 2-216 None
A0A1Z3HTC3 117-258 None
A0A6J4LAZ5 45-210 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.