DPCstruct | MC10592

Metacluster Properties and Pfam Annotations

Number of structural domains80
Mean domain length (aa)257 ± 75 aa
Standard deviation of domain lengths75.30
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score78.71
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)29.99
Pfam Score98.36
Assigned Pfam label(s) PF03469- CL0221- PF12165

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453ELM7 4-224 LEKELHEKRELELEVTRLNGTLQVMKHLEGDDDGDIHDKMEKLSEKLEHERKRLEELSGELVRKERESNDELQEARKELIMGLEDIL…
A0A5D2JAK8 18-263 CSLIYEINCKKEQLSQMEREYNEMTATLRGLINGLIAKINSKDSNLWGWELQYNVTVSQLNGKNAALRLAFAQVYSKKKKKKKTNGN…
A0A565CCV5 2-181 None
A0A443NDX2 290-631 None
A0A6D2I1H8 2-179 None
A0A453DZX0 165-336 None
A0A6D2JJP9 893-1205 None
A0A061RPA8 142-513 None
A0A843X423 69-245 None
A0A3Q7F588 46-340 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.