DPCstruct | MC10527

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)144 ± 28 aa
Standard deviation of domain lengths28.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.22
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)35.97
Pfam Score100.00
Assigned Pfam label(s) PF00864

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7M4EGT8 7-140 EKVSSFLFEYDTPRMVLVRNKKVGLTFRLIQLVVLGYIIGWVFLYEKGYQSQDGIVSSVSVKLKGLALTNVSGMGPLIWDVADYVFP…
A0A212DIP4 3-138 CISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQSEEK…
A0A4Z2GI03 5-156 None
A0A267GC16 8-142 None
Q6P5P0 6-132 None
A0A6P8FTL5 1-122 None
G3I1N5 5-121 None
A0A2Y9E1E3 315-480 None
B7Z1M5 11-131 None
A0A818EQS2 24-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.