DPCstruct | MC10399

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)208 ± 17 aa
Standard deviation of domain lengths17.03
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score83.07
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)32.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E1X1G6 471-670 KRDTSIKEIRSVITNKDYQTKTAVQFMGEIDSRKSEITKLYNLTDHEYNELSKLAFGILGNESQFGESSRYHVKEALPWLVAIAKGN…
A0A7H9MNE5 1-197 MLVPNSDEVQTIQVRRFIQALAVNKIELQKMYKVSGDEYTLLAQMSVGILGRETRFGESARYKVKETMPWAVSLAKVMRSVTTGKGV…
A0A162FXN5 177-366 None
A0A2E3XU41 270-472 None
T0RMU8 350-541 None
A0A514XDY0 46-259 None
A0A1F6UQU5 360-547 None
A0A2E3VWC2 518-757 None
A0A2E5CA00 845-1081 None
A0A514WSE4 5-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.