DPCstruct | MC10294

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)86 ± 9 aa
Standard deviation of domain lengths9.07
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score78.96
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)40.43
Pfam Score100.00
Assigned Pfam label(s) PF09796

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q4WQL8 8-90 MKRIHYPTYKSPYGPKYHYQPHVAGLSLKQLSTLGMKSAAFGGVALFTVLYYASGIPRVQRDILQKLPVIGNNFVHEIPASDN
A0A318ZT55 15-93 AGGYRSPFGPKYSTPLHWHGLTARSAVTAGTIAAGFGVSAGTFLLFFFGEVPRVRRDILQKLPFLDEYFDRTVAPEDNP
A0A2B7X597 125-206 None
F2SQK7 63-152 None
A0A225AAS4 10-98 None
Q2U055 1-70 None
A0A1E3PJF1 1-79 None
A0A2C5XAD5 32-135 None
A0A2B7Z1T7 1-77 None
A0A7D8Z1I8 8-97 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.