DPCstruct | MC10249

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)222 ± 30 aa
Standard deviation of domain lengths29.63
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score73.12
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.68
Pfam Score100.00
Assigned Pfam label(s) PF08728

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A168KZ05 244-422 HLVRMYEKDLEMRSLQTNDLGDEKEIGIHCPNVLTFGSFPDRNLRPYFRATSRLSMVMHVPELSLVIIGSPMGRVLLLTPTRLPSPQ…
B2W2I2 236-414 VSLIKPSNPFLIITKEEIFLFQSPQVKQGQSRPECVVTMRRPLHPGEWSLDLVPEDRHCYFAQIPELGVFLVGSPIGRVGVFTLYWT…
A0A2N6NEM3 4-221 None
A0A094FV33 23-240 None
A0A0M8MZ72 127-311 None
M1VWJ3 530-785 None
A0A4U0XRC7 934-1151 None
S3C8L8 820-1039 None
A0A842ZA80 306-507 None
A0A7C8R3K4 281-549 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.