DPCstruct | MC10149

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)120 ± 11 aa
Standard deviation of domain lengths10.82
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score91.20
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)34.11
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A847HZE1 193-308 LPVSDAPYRLTVPYVADVAELREHLANHRVRQAVALYRQPLLPLSEAPGVVEEREGLEEELRQAVLLSRDADALCELAERLGDDLET…
A0A7Y5JXK2 18-136 LASRPYRLVAGLAGDWLAVEAHLAAGDVASAMRAYRGPLLPRSVAPGVVRLRESIEGDVRTAILRSGRADLMSAWTRSASGADDYEM…
A0A358H0R8 1-108 None
A0A6F8XVV8 162-289 None
A0A1G9Z4X7 440-570 None
A0A7C2FWT3 294-412 None
A0A1G8P5R0 323-441 None
A0A4Y4DQT9 126-240 None
S4N1B0 1-101 None
C8XCD7 396-529 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.