DPCstruct | MC1013

Metacluster Properties and Pfam Annotations

Number of structural domains1422
Mean domain length (aa)163 ± 26 aa
Standard deviation of domain lengths26.40
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score85.31
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.45
Pfam Score97.59
Assigned Pfam label(s) CL0125- PF13376- CL0268- PF16169- PF07589

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y4LFG3 101-271 TIHGLPYYAQNDPRWAYTVIGGRFFSGTGCAPTVITSIVNYYLNANLTPYQIGLELNRLGYFNTDVLAGTSSDCWNWVSSNYGFNIK…
A0A1G2EXB2 15-161 PDMKKLKIPYYRQETDYFCGPAALKMALEFFGKKVSQKKLAGLLKTNEKRGTLRRDMIKTARGFGLSARGFFGKNLDEVKKFLNTGN…
A0A6L3F270 248-448 None
A0A5Q2RLK1 656-829 None
A0A6L7ABI5 310-472 None
A0A2E8K291 9-167 None
A0A822E1J4 6-132 None
A0A7J0FUM6 11-143 None
A0A7Y5SGY9 262-460 None
A0A7Y4ZNT6 110-331 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.