DPCstruct | MC10046

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)227 ± 21 aa
Standard deviation of domain lengths21.29
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score79.52
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)25.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q4U930 664-887 KNLKWALSTMLMIIPTTIIFYFLFDGVLPHAIIIDEESKHIVVMTSLADFLGTMPPVVMTSKKHEYRYWTWENSCFWIAVIPQIAVL…
A0A2T7IKU8 1-263 MTFFRTLSHAFSPLMMIFVSSLIKDFLFPNLLPYALLSKFRWNFVTVMSSILKLIGPVLLFSLESNSLFPKWDTPYNAFWIIVVPMA…
Q4N1Y7 1026-1242 None
Q4N1S5 368-591 None
Q4MYC4 445-670 None
L1LC13 789-1024 None
S6AZ02 2-227 None
A0A2T7ISW2 118-333 None
A0A2T7IQ65 1-231 None
A0A2T7IG38 45-302 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.