DPCstruct | MC10043

Metacluster Properties and Pfam Annotations

Number of structural domains716
Mean domain length (aa)166 ± 31 aa
Standard deviation of domain lengths31.04
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.26
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)14.02
Pfam Score91.83
Assigned Pfam label(s) CL0349- CL0063- CL0221- CL0113- PF02310

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M2Y9L3 108-277 REATNISRQVVVFWDIENCAVPSSVSGNYVVHKLLRRMKLFGDIISIRVYACMELLKTELKLALQTSGVELIDARRDNWVVQSRCYD…
U1NXQ3 3-99 QRLYLDEHATPNLLRAAEERGFEVITTSGDVDVRLAVDATATAVENTIDVLVLVSRDADFKPALERAATRGVRTVAIAPGSYGRSDA…
M4D0Y5 1-152 None
M4D5K9 230-418 None
M4DE77 322-472 None
A0A5B8MF83 142-299 None
A0A1L9PM54 281-510 None
A0A5C3MBS8 15-194 None
A0A2P4ZBJ0 60-278 None
A0A397SEC2 129-309 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.