DPCstruct | MC10004

Metacluster Properties and Pfam Annotations

Number of structural domains248
Mean domain length (aa)323 ± 104 aa
Standard deviation of domain lengths103.70
Length coefficient of variation0.32
Mean AlphaFold2 pLDDT confidence score82.03
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.55
Pfam Score97.16
Assigned Pfam label(s) PF00118- PF04782- PF05699- CL0026- PF00079

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G9XYX0 4-188 YRFDRGYASPYFINDQESNSAILEEPLILLAEDTLATHADVLSILDSVAKTGRSLLIIAHDTEGPAMEMVVINNSRRTVKAAVVKAP…
H9H0X6 45-374 ALDDMIHVLKKISTPVDVNNREMMLKIIKSAINTKAINRWSELACSIALDAVRTVELEENGRKEIDIKKYAKVEKIPGGFSEDSCVL…
A0A1Z5SAH0 549-1058 None
A0A445CCV5 12-238 None
A0A2C9KF69 2-221 None
A0A7E5W020 386-598 None
A0A1V6T0Q3 487-894 None
A0A835E4L9 341-581 None
A0A835AIR4 126-561 None
B7Z532 2-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.