DPCstruct | MC10000

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)378 ± 50 aa
Standard deviation of domain lengths49.64
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score70.71
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)21.27
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I0Z1J8 19-349 QRAPPDFSDLASPPIDWSLKSRALFLSVQPFSICQEALMAPSSVAFDTLSSFARGSQPGPSCQEQFQHALMTWQHPESSLPGAAVSA…
G1NNW6 40-324 SSQPFTWAEHLKAQEEAQGFAQHCRAAEINLPQSVQEPKLSTELRCAFQQSLVYWLHPSLSWLQLFPRIGADRKIAGKACPWAQDEA…
A0A7M5WXI6 90-500 None
A0A5F5XSP0 126-546 None
A0A2K1ICA2 238-667 None
A0A3P8SXE1 63-475 None
A0A4U1EYH4 686-1082 None
A0A0N5A4V6 37-398 None
A0A7S0BPT5 1-340 None
R1FEP1 1-455 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.