DPCfam | MC90136
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 423 |
|---|---|
| Mean domain length (aa) | 223 ± 51 aa |
| Residues in low-complexity regions (%) | 4.13 |
| Residues in coiled-coil regions (%) | 0.33 |
| Predicted disordered residues (%) | 16.46 |
| Average transmembrane regions | 0.14 |
| Dominant Pfam architecture(s) | PF07899 |
| Sequences matching dominant architecture (%) | 95.93 |
| Average overlap percent | 90.59 |
| Pfam Overlap Label | Equivalent |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| F6HER2 | 8-255 | 248 | RYIMDHPNDRETLRSELLDAFQVARDPAKMVLDALTGFFPSNANEDGSSELHTMRRSCVFMLEQLMLFSPEIGEDVRQRAKSLAQ... |
| C7IZL5 | 124-272 | 149 | HMGRICERMGSGELLRFVISRMGDLSWLLRAVPPALRRAPNPAELVLRAIGRYYIRPGGRHTEAACELLLLSYVRAGCPLRPGQE... |
| UPI0007EC3D1E | 401-541 | 141 | LMNEHWTRTDFVCSEIAAVLQASSXPAKLVLDAMQGFYPSNRTVDTTEFVYDLTVIRRSCVLLLQQLKRFSLQINPQVRKEARAL... |
| A0A022S297 | 493-650 | 158 | LTVKMDGKTLQMFLNDPQKDLESMGDEIYTVLHLSSDPPKLVLDAMVGFYPPHLREEDVEFNVRKTCIILLQQLIRMSPKIQPYV... |
| A0A022RU33 | 329-497 | 169 | ELFMHNTEKDLEFFSDEVFKVLLRSSDPAKLILEAVVLFCAPPYVKDGDIKIDIQERGIVLLDQLTKMSPDILRCGREAAILVAN... |
| A0A078HTL8 | 358-574 | 217 | RHEVSSVLRATPNPAGFVLEQVQDGIRQGSTFQDTFLETLVLIFEELVKIQGPDESQLLQLQATEVATLWKERITIEAPKSTLEA... |
| D7TUW9 | 1-168 | 168 | MKLAVDWKEKFVKKYEVPQKFLGFYLLLAIYGLASSFDPDELLGLLMNMDHSKKLRVTPDLCLALGLADKIPNYIQDLIERNLLS... |
| A0A1S4CUC9 | 48-334 | 287 | QLETLCKTMCGKGLRTYIISQLPLPEQENTLREQLSEALKLAPNAAKLVLSCVGDFYAKRGKDLNKDTQMISYREASALVLECFL... |
| A5AIV0 | 80-349 | 270 | LKYLCLNMDGKGLRSFLIEKTKARPPFSIGDEVSAALLSAPDPAMLVLDAVDGFYPXKSKSKGKDKRSELVDIRRTCVLLLEXLM... |
| W9R449 | 253-495 | 243 | ELKSLCINMDGKSLRLFLYNHAAEHDFICSEVCDALQYASDPAKLVLDAIPGILSSQPDFDKSLSLNKVRKSCVLLLEQLINISP... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-Q5XV31-F1 | 188-441 | 96.18 | 75.65 | View in AlphaFoldDB ↗ |