DPCfam | MC50353
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 1344 |
|---|---|
| Mean domain length (aa) | 60 ± 6 aa |
| Residues in low-complexity regions (%) | 2.36 |
| Residues in coiled-coil regions (%) | 0.0 |
| Predicted disordered residues (%) | 17.86 |
| Average transmembrane regions | 0.05 |
| Dominant Pfam architecture(s) | PF01963 |
| Sequences matching dominant architecture (%) | 99.8 |
| Average overlap percent | 24.75 |
| Pfam Overlap Label | Reduced |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| UPI000846237A | 228-280 | 53 | EGFRTKILTDRNRRWADEIERLMDGSGTLFIAVGAAHLAGATACRRSWRKRGL... |
| A0A105V3W6 | 274-330 | 57 | AAFQEGMVTDRNLAWRPVLHGILDKGHAVVVMGAGHLGGPQGIIALLRADGYTVEPV... |
| F6GGL1 | 233-289 | 57 | ESKKRFLDDRNIKWIPKIGEFSREHSVFYGVGAAHLGGEQGVINLLKKAGYKVTPVL... |
| S5CE15 | 234-296 | 62 | KRESPTSYDDVFTKRNQNWLPQIEAMFGDEDQEFVLVGAGHLVGDDSVIALLEAKGYKVEQM... |
| A0A1C2C099 | 293-346 | 53 | QSLGPDRNRDWMKHIPTYIKNKSTFIAVGAAHLPGEEGLIQLLRDAGYTVEPM... |
| D8JWL0 | 267-324 | 58 | ASLREELVSKRNERMIERALPLLDQGSVFIAVGAMHHLGPHGLVALLRERGFAVTAIE... |
| W0AF92 | 229-292 | 64 | ELSLSPELADALKRQRNAAWAARLQKALDQPGTVLVAVGAAHLAGKDSVQEMLEARGIKVKRVQ... |
| A0A0S2DJD2 | 255-312 | 58 | YRIVNVERNEAWVPQIQKLLDEQKKGDTLVVVGSLHLLGNDGLVERLRAKGYKIERIC... |
| UPI000648D89C | 258-321 | 64 | KTALERATLKAMLDDRNPAMAARIDALHAGGKNVFAAVGSLHMFGKSGLPALLARRGYKVERIE... |
| A0A1J5R0F5 | 270-328 | 59 | ELMKRILDDRNPKLADRIDALHMSGKRVFAAVGSLHMFGVTGLPMLMSKHGYVVERIEL... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-E7F4V6-F1 | 297-356 | 95.00 | 94.83 | View in AlphaFoldDB ↗ |