DPCfam | MC44776
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 340 |
|---|---|
| Mean domain length (aa) | 59 ± 7 aa |
| Residues in low-complexity regions (%) | 5.58 |
| Residues in coiled-coil regions (%) | 3.32 |
| Predicted disordered residues (%) | 49.88 |
| Average transmembrane regions | 0.01 |
| Dominant Pfam architecture(s) | PF02978 |
| Sequences matching dominant architecture (%) | 99.68 |
| Average overlap percent | 48.91 |
| Pfam Overlap Label | Reduced |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| A0A1J4VC04 | 369-432 | 64 | EAIILSMTKEERRNPELINVSRRDRIAKGSGSKPDDVHRLLKQFRQAKEMMSVFSGGKKISKKI... |
| A0A1G2Z565 | 78-144 | 67 | EAIVYSMTPQERRDPDLIDSSRRRRVAAGCGMEPNDVSSLVKTFTRSRDMMKALSGGSFGGLKSLFS... |
| A0A0S8JHQ4 | 373-433 | 61 | EAIVCSMTREERRRPEILDGSRRKRIAKGSGTTLHDVNNVVKQFMMARKLMKDVTTGKLKV... |
| D1JEY5 | 373-428 | 56 | MTEDELSEPKIISGSRLRRIAHGSGTSTAEVNELIKYHRMMQKMMKSISSGRGNMP... |
| A0A0S8FWM9 | 374-429 | 56 | EAIINSMTPEERSTPEVISASRRQRIARGSGSEPVVVNQLLKQFKQMKKVMRKVSR... |
| A0A1L9ASM5 | 375-428 | 54 | AIINSMTEKERQNPDILNGKRRLRISKGSGTSVTDVNLLIKQYNQMSSMVNKFS... |
| T1CD47 | 41-95 | 55 | MTPRERVSPALIDGSRRRRIARGAGVQVQDVNRLMKQFLQMQKMMKQMRGGAHAP... |
| A0A1V8ND60 | 375-430 | 56 | SIINSMNKNERKYPEKIKKSRKRSIAYGSGTKIQDVNVVLRQFFEMKKLNQKMQKN... |
| A0A094PHP1 | 25-79 | 55 | AIIQSMTPAERKDPSVLNASRRARIAAGSGRTVTDVNQLVDRFTQARKMMKQMAK... |
| T2DM64 | 370-426 | 57 | KIKRYMTMMDSMTNEELDSSNPKLMNESRIMRIARGAGRQIREAMEMMEEYKRLAKI... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-O67615-F1 | 365-425 | 95.31 | 90.14 | View in AlphaFoldDB ↗ |