DPCfam | MC353988
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 1247 |
|---|---|
| Mean domain length (aa) | 64 ± 9 aa |
| Residues in low-complexity regions (%) | 1.25 |
| Residues in coiled-coil regions (%) | 0.04 |
| Predicted disordered residues (%) | 9.79 |
| Average transmembrane regions | 0.14 |
| Dominant Pfam architecture(s) | PF04578 |
| Sequences matching dominant architecture (%) | 98.94 |
| Average overlap percent | 79.28 |
| Pfam Overlap Label | Extended |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| A0A1E5WG49 | 514-583 | 70 | VLKNGAWLGKQLVNLQTGWGALARFWSEMILYVAPSENLDGHAEAIACGGELITLLWALLAHAGIASRET... |
| I1HUS5 | 693-761 | 69 | GGRLGKKLTEEEPALRWTVLSEFWAEMMLYVAPCEDAQARAHLEALARGGEFITHLWALLTHAGVLKRE... |
| A0A1E5WMJ4 | 377-444 | 68 | ELGGKLGRELRGVVPEERRWKVLADFWAEFILFLAPSSNVEIHAEKLAAGGEFMTHLWALLTHAGILE... |
| A0A1D5SCX5 | 293-364 | 72 | HQVLKDGAELGRRLAELPAGEEVAWKTLAEFWSDTLVYVAAACDNIDDHAEAVARGGELVTLLWALLAHVGS... |
| A0A199UWP0 | 685-739 | 55 | MGERKWGVMSAVWMEMLAYTACHCQAREHARQLSCGGELATVVWLLMAHVGLGKL... |
| T1N8I9 | 308-358 | 51 | KEDVVYALLLLWVDFLAYAANRCNREAHARKLGSGGELLTVIWLYQEHLHQ... |
| A0A1D5U185 | 588-646 | 59 | LGYELDDPTRKWEVIKGVWMEMLCFSASRCQGYWHAETLGTGVEFLSYVWVLLQYSGME... |
| M0XD94 | 499-568 | 70 | AALLGGQLGAAVGEDDRRRWAVLAEFWAELVLFLAPSDNVDIHAEVLGAGGEFMTQLWALLAHAGVLERP... |
| A0A199VWU4 | 525-597 | 73 | TIISKGVKLGKQLMNDVKEDAERWELLERFWAELILFLAPSKDAMAHASKLEEGGEFITQLWALLYHARVEER... |
| M0VVE3 | 530-593 | 64 | AAVIAVELLKADDLKMPELLELVFNIWVDKLLYAGTRCSRESHARQLGHGGDLTTIIWIMAEHA... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-I1NHV3-F1 | 629-702 | 98.59 | 92.54 | View in AlphaFoldDB ↗ |