DPCfam | MC353988
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 1247 |
|---|---|
| Mean domain length (aa) | 64 ± 9 aa |
| Residues in low-complexity regions (%) | 1.25 |
| Residues in coiled-coil regions (%) | 0.04 |
| Predicted disordered residues (%) | 9.79 |
| Average transmembrane regions | 0.14 |
| Dominant Pfam architecture(s) | PF04578 |
| Sequences matching dominant architecture (%) | 98.94 |
| Average overlap percent | 79.28 |
| Pfam Overlap Label | Extended |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| A0A1D5ZZE0 | 470-529 | 60 | LAQQLLTMRTPDMTTLHMILDVWVEMLCYAAYWCNENFHAKHLNDGGELMTIVALFILYY... |
| Q7XL35 | 285-324 | 40 | SVEFLFKVWVEMLHYVSHRCSRESHAKQLSSGGWLVTLVL... |
| J3MR92 | 526-567 | 42 | DVWVRLLIYAASKSRREAHAAQLARGGELLTFVWLLMQHRGI... |
| Q8LIL8 | 631-696 | 66 | DAWSIAEELLKLEDDEKMWRVIEGVWVEMLCFSAARCRGYLHAKGLGTGVEFLSYVWLLLHYMGME... |
| K4A0Q3 | 588-660 | 73 | ETIYRKGLRLGEQLKNMQADHCWEVLAGFWAEMLLYLAPSNNVKEHVECLAKGGEFITHLWALLTHAGILDRG... |
| A0A078HPC6 | 621-685 | 65 | LAKELKRLDENGKWRVLSKVWVELLSYAASHCKATEQVAQLSRGGELLNFVWLLMAHFGLADQFQ... |
| I1LCL7 | 609-671 | 63 | SLEREKKWSKEEKWEMMSHVWVEMLCHAASQCRGFHHAKQLSRGGELLTHVWFLMAHLGITEQ... |
| A0A0E0JXV8 | 5-57 | 53 | DGGKRLRVIGGVWVEMICYSASRCRGFLHLKSLGVGGEFLTVVWLLLHRMGME... |
| A0A0E0BM67 | 462-529 | 68 | VVGGRLANNLIEIEHPGDRWKVLCDFWAEMMLYIAPSNDAKAHLETLPRGGDFITHLWALLTHGGILE... |
| A0A0D9WV88 | 601-674 | 74 | RNGAKLAEQLVVLIQTQEENEGTAWEVLSGFWSEMILFIAPSDNLDGHVEAIARGGELITLLWALLTHVGIISR... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-I1NHV3-F1 | 629-702 | 98.59 | 92.54 | View in AlphaFoldDB ↗ |