DPCfam | MC295259
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 2049 |
|---|---|
| Mean domain length (aa) | 160 ± 16 aa |
| Residues in low-complexity regions (%) | 2.66 |
| Residues in coiled-coil regions (%) | 0.0 |
| Predicted disordered residues (%) | 14.37 |
| Average transmembrane regions | 0.02 |
| Dominant Pfam architecture(s) | PF14579 |
| Sequences matching dominant architecture (%) | 89.47 |
| Average overlap percent | 54.62 |
| Pfam Overlap Label | Extended |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| T1DRX1 | 798-946 | 149 | LQKIWADWKKFTQYAFNKSHATCYSWVAYQTAYLKAHYPSEYMAGALSRNLNNITEITKLMDECKSMKIQVLVPDVNESDYKFSV... |
| A0A1E7XAA5 | 716-863 | 148 | DKVFDYIERFANYGFNKSHAVAYSKMAYELAYLKVYYPGEFHVALLNSVNNNSVKIKEYLLDAKSMGVKVDGPNINASDAGFTFQ... |
| UPI0007E5CC14 | 297-475 | 179 | MRANGYPEEFAERIYQQLEGFGSYGFPESHAASFAILAYSSSWMKCTHPDVFLASLLNSQPMGFYAPAQLVRDAREHGVEIWPVC... |
| A0A0R1MIY6 | 15-195 | 181 | TMIEKYNDTKEHAEEVADRFIQIFMDAANYGFSVNHSLPYSYVGYIATWLRYYYSLEFATSAFEIWKDDQNKINKVSSYAQEHGI... |
| W4VIL2 | 128-279 | 152 | VRFSNYGFNRSHAVAYSIIAYQLAYLKANYPVSFFAEMLSSNIGNTDKIQGYIREAKNHNIKVLQPSINHSIGRFRVENNTIRIG... |
| A0A136LP27 | 339-508 | 170 | ERIFEDIEFFANYGFNKSHAADYAVITVQSAFLKAHYAPEYMAALLTVYFDAADKVTTYLAECMRLSIPILPPSINASALDFDIE... |
| R7PQV3 | 624-818 | 195 | IEEANVPQWFIDSCLKISYLFPRAHAVAYVMMAFRIAWFKINYPLAFYAAYFTIRAEGSFDALIILRGFEAQKAELHRVATMEHP... |
| U6DZL0 | 1-139 | 139 | WFKVHAPLLFYSGYFSKRAEQFDHKIMISNDVVAVTKKIEALNKLKANKQIKAKDEILINTLKIAKEMLQRGFKFLSVDFNKSDI... |
| H5SI67 | 724-888 | 165 | AKAEELFADIEKFARYGFVKAHSTAYALISYWTAYLKAKYPTCYLAALLTSVAGNTEKIAEYIQECRELGITVLPPDINESDADF... |
| A6GPV8 | 752-927 | 176 | KQLFDLMEKFAEYGFNKSHSAAYALIAYHTAWLKAHYPAEFMAASMSSDMDDTDKVKIFVEDAMAMCQVPGKKAGTTVTMLGPDV... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-Q9XDH5-F1 | 800-949 | 96.55 | 91.70 | View in AlphaFoldDB ↗ |