DPCfam | MC2885
Metacluster Properties and Pfam Annotations
| Number of UniRef50 seed sequences | 4418 |
|---|---|
| Mean domain length (aa) | 56 ± 10 aa |
| Residues in low-complexity regions (%) | 0.83 |
| Residues in coiled-coil regions (%) | 0.0 |
| Predicted disordered residues (%) | 12.4 |
| Average transmembrane regions | 0.01 |
| Dominant Pfam architecture(s) | PF00188 |
| Sequences matching dominant architecture (%) | 90.51 |
| Average overlap percent | 25.55 |
| Pfam Overlap Label | Shifted |
Seed Sequences
| Protein ID | Range | Length | Seed Sequence |
|---|---|---|---|
| H2RIB7 | 1-61 | 61 | LVWATSSQLGCGRHLCSAGQTAIEAFVCAYSPGGNWEVNGKTIVPYKKGAWCSLCTASVSG... |
| K4I262 | 135-197 | 63 | GHYTQVVWYRSYILGCAVAHCPRQKTYKYFYVCQYCPAGNLRSQIYTPYKIGRPCRDCPQACD... |
| H6U749 | 329-378 | 50 | ASHFTQVVWKATTQVGCALASCDGLLKGFGKARYYVCEYTPQGNVGGQFA... |
| UPI000333D798 | 83-151 | 69 | HYTQVVWADSYKVGCAVQFCPRVSGFDTLYNGAHFICDYGPGGNYPTWPYKRGATCSACHTNNTCLDNL... |
| A0A151W550 | 127-178 | 52 | YTHWTQIVWKSTTQVGCARSRCNNLLGRSTGTATYYVCFYNPAGNVIGQAPQ... |
| A0A164YM61 | 525-569 | 45 | ECGHYTQIVWRQTRRVGCARVNCFGGRGVFMTCNYDPPGNYIGEK... |
| F4R747 | 257-318 | 62 | SHFTQVVWRGSRRVGCAITQCNYVGRFEGSRVYQQMGRKVPNIACVYFPAGNVIGQFPQNVI... |
| A1BQQ5 | 154-213 | 60 | GHYIQQIYAEASRIGCGQSACGEDRYFVCNYYKSTMGNTPYAQGSRCGQCPNSCWEELCD... |
| A0A0N5BLQ6 | 205-257 | 53 | GSVRTRHFTAMVWKSVKQIGIGIFQEGNEIYVKLIYDKTVNLPNQFEKNVLKK... |
| A0A1W2WCS3 | 138-205 | 68 | GHYTQLVWGISYKVGCGMTTCDQVDIGGTIHNTPTIVVCNYVPGGNFSPVPYKRGPACSLCQTGQICI... |
Representative AlphaFold Structure
| AlphaFold ID | Sequence Range | HMM Coverage | Avg pLDDT | AlphaFold 3D Structure |
|---|---|---|---|---|
| AF-A2CF32-F1 | 98-144 | 81.82 | 89.06 | View in AlphaFoldDB ↗ |